At its worst, the east side is living, breathing highway full of trash, homeless and obnoxious people and just extended New Jersey.
Philly is mostly a dump but there are good parts that are worth visiting at some point. The crime and drug problem there is extremely sad and I hope there's a future where it improves.
In the west it's hickville but Pittsburgh has some nice parts to it. The Pirates suck but they have a top 5 park in baseball. Love the concept of the bridge.
It's not too bad of a state to live in even outside the cities. The weather is about the same as anything else on the east coast which is fine.