AdreN, one of the most experienced players in the CIS region, has been on Gambit's books since January 2016, when his team, featuring three-fifths of the current line-up, signed for the UK-based organisation.
He played a key role in Gambit's victories at DreamHack Open Austin 2017, PGL Major Krakow and ROG Masters, breaking into the top 20 player of the year ranking for the first time in his career.
"It is time for a change, both for him and our CS:GO roster," Gambit CGO Konstantin Pikiner said in a statement.
"With that in mind, we support his decision to prove himself in another team, possibly in another region."
Gambit have over a month to find two players to complete their line-up as they will make their next LAN appearance only at the end of November, at the $150,000 SuperNova CS:GO Malta.
The CIS team currently have:
Andrey "B1ad3" Gorodenskiy (loan coach)
Gambit Esports announces an opening of transfer negotiations concerning Dauren "AdreN" Kystaubayev of Gambit CS:GO pic.twitter.com/nxhKjZyRJh— Gambit Esports (@GambitEsports) October 16, 2018